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Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent

Dev, Selvi and Prabhakaran, Praseetha and Filgueira, Luis and Iyer, K. Swaminathan and Raston, Colin L. (2012) Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent. Nanoscale, 4 (8). pp. 2575-2579. ISSN 2040-3364

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Official URL: http://dx.doi.org/10.1039/c2nr11502f

Abstract

Curcumin nanoparticles of less than 50 nm in diameter are accessible using a continuous flow microfluidic rotating tube processor (RTP) under scalable conditions, at room temperature. A mixture of DDAB and Pluronic F127 renders higher stability of the curcumin nanoparticles in physiological pH 7.4 for up to eight hours. The nanoparticles have enhanced cytotoxicity in estrogens receptor negative and positive breast cancer cell lines compared with free curcumin.

Item Type:Article
Uncontrolled Keywords:curcumin, cancer theraphy, cytotoxicity
Subjects:T Technology > TA Engineering (General). Civil engineering (General)
Divisions:Biosciences and Bioengineering
ID Code:47211
Deposited By: Narimah Nawil
Deposited On:22 Jun 2015 05:56
Last Modified:31 Mar 2019 08:34

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