An efficient pattern recognition based method for drug-drug interaction diagnosis

Abstract

The diagnosis of interactions between two drugs is an essential procedure in drug development. Many medical tool's offer inclusive records related to DDI. However, this tool's results are not very satisfactory. The main aim is to propose an efficient approach based on pattern matching that identifies the interaction between two drugs. In this study, the goal is to collect the data from the DrugBank, which is a publicly available source. The drug-related data includes drug ID, drug names, and various kinds of sentences of drug-drug interaction. Drug names will be identified by drug names dictionary defined in the corpus, and sentences will be determined according to given patterns. These sentences will treat as input data, and preprocessing steps will perform in these sentences. Various types of features are selected for machine learning classification. Then all the attributes will be classified into desired classes. The proposed method gains 95.4% accuracy from the random forest classifier.