Effect of calcination temperature on structure of mesoporous borosilicate bioglass

Abstract

Recently, most researchers have been focusing on the development of the mesoporous bioactive glasses for medical application. These materials are capable for bone tissue (soft and hard) regeneration and the delivery of bio-responsive active therapeutic molecules such as drug, proteins, nucleic acids, and peptides. However, the structure properties of the mesoporous bioactive glass are easily been controlled with a small change of calcination temperature during the sample preparation. In this perception, a series of mesoporous borosilicate bioactive glasses (MBBGs) with the composition of 10B2O -70SiO2 -15CaO- 5P2O5 were prepared using the combination of sol-gel and evaporation induced self-assembly (EISA) and characterised. The calcination temperature of the bioactive glass preparation was controlled with varied temperature of 400 C, 500 C, 600 C and 700 C. The amorphous nature of the prepared samples were confirmed using XRD pattern. The EDX and FTIR spectra shows a small amount of carbon trapping inside the sample is increases with the increased of calcination temperature. All MBBGs samples show a ratio of Si-O-NBO and Si-O-Si (sym) bigger than 1. It is established that the structure of the mesoporous borosilicate bioactive glass can be tailored by controlling the calcination temperature.