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Adaptive DNA computing algorithm by using PCR and restriction enzyme

Watanabe, Shinpei and Tsuboi, Yusei and Ibrahim, Zuwairie and Yamamoto, Tsuneto and Ono, Osamu (2004) Adaptive DNA computing algorithm by using PCR and restriction enzyme. In: 2004 Ieee Conference On Cybernetics And Intelligent Systems. IEEE Conference on Cybernetics and Intelligent Systems , 1 . IEEE, USA, pp. 262-267. ISBN 0-7803-8643-4



In this paper, we introduce a new adaptive DNA coinpitting algorithm by using Poiymcruse Chain Rearlion (PCR). The adaptive algorithm is designed based on Adleman-Lipton [3I paradigm of DNA computing, However, unlike the Adleman- Lipton architecture, a cutting operation has been introduced to the algorithm and the mechanism in which the molecules used by computation were feedback to the next cyclc was devised. Morcovcr, amplification by PCR is performed in the molecule used by feedback and a concentration difference arises in the base sequence can be used again. By doing this, the molecules which serve as a solution candidate can he narrowcd down and the optimal solution can be detected easily. From the application point of view, a simulation has been carried out on the shortest puth problem and the validity of the proposed adaptive algorithm is stated from the results of the simulation. Finally, we go on to propose applying adaptive algorithm to the chemistry experiment which used the actual DNA molecules for soiving B universal problem.

Item Type:Book Section
Additional Information:ISBN: 0-7803-8643-4 IEEE Conference on Cybernetics and Intelligent Systems Singapore, SINGAPORE, 01-03 Dec, 2004
Uncontrolled Keywords:adaptive algorithms, algorithms, computational complexity, computer simulation, enzymes, feedback, polymers, product design, DNA computing, polymerase chain reaction, restriction enzyme, shortest path problem, DNA
Subjects:T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:Electrical Engineering
ID Code:9792
Deposited By: Zalinda Shuratman
Deposited On:25 Mar 2010 04:15
Last Modified:15 Aug 2017 04:06

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