Faheem, F. and Kumar, B. K. and Sekhar, K. V. G. C. and Kun-Jiappan, S. and Jamalis, J. and Rafael, B. F. and Sankaranarayanan, M. (2021) Recent update on the anti-infective potential of carboline analogs. Mini-Reviews in Medicinal Chemistry, 21 (4). pp. 398-425. ISSN 1389-5575
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Official URL: http://dx.doi.org/10.2174/138955752066620100113011...
Abstract
β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral, antibacte-rial, antifungal, antileishmanial, antimalarial, neuropharmacological, anti-inflammatory and anti-thrombotic among others. β-Carbolines exhibit their pharmacological activity via diverse mechanisms. This review provides a recent update (2015-2020) on the anti-infective potential of natural and synthetic β-carboline analogs focusing on its antibacterial, antifungal, antiviral, antimalarial, antileishma-nial and antitrypanosomal properties. In cases where enough details are available, a note on its mechanism of action is also added.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | antibacterial, antifungal, antiprotozoal |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Science |
| ID Code: | 96513 |
| Deposited By: | Narimah Nawil |
| Deposited On: | 26 Jul 2022 08:01 |
| Last Modified: | 26 Jul 2022 08:01 |
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