Universiti Teknologi Malaysia Institutional Repository

Effect of short-term ketogenic diet on end-tidal carbon dioxide

Vijayam, Bhuwaneswaran and Malarvili, M. B. and Md. Shakhih, Muhammad Faiz and Omar, Nashuha and Abdul Wahab, Asnida (2021) Effect of short-term ketogenic diet on end-tidal carbon dioxide. Clinical Nutrition ESPEN, 42 . pp. 124-131. ISSN 2405-4577

Full text not available from this repository.

Official URL: http://dx.doi.org/10.1016/j.clnesp.2021.02.005


Background & aims: Previous studies have shown that end-tidal carbon dioxide (EtCO2) is lower with the presence of supraphysiological ketones as in the case of chronic ketogenic diet (KD) and diabetic ketoacidosis (DKA). This study aimed to determine changes in EtCO2 upon short term KD. Methods: Healthy subjects were screened not to have conditions that exerts abnormal EtCO2 nor contraindicated for KD. Subjects underwent seven days of KD while the EtCO2 and blood ketone (beta-hydroxybutyrate; ß-OHB) parameters were sampled at day zero (t0) and seven (t7) of ketosis respectively. Statistically, the t-test and Pearson's coefficient were conducted to determine the changes and correlation of both parameters. Results: 12 subjects completed the study. The mean score ± standard deviation (SD) for EtCO2 were 35.08 ± 3.53 and 35.67 ± 3.31 mm Hg for t0 and t7 respectively. The mean score ±SD for ß-OHB were 0.07 ± 0.08 and 0.87 ± 0.84 mmol/L for t0 and t7 respectively. There was no significant difference of EtCO2 between the period of study (p > 0.05) but the ß-OHB increased during t7 (p < 0.05). There was also no correlation between the parameters. Conclusions: These findings suggest that EtCO2 may not be utilized to determine short term nutritional ketosis.

Item Type:Article
Uncontrolled Keywords:Capnograph, EtCO2
Subjects:Q Science > QH Natural history > QH301 Biology
Divisions:Biosciences and Medical Engineering
ID Code:95530
Deposited By: Widya Wahid
Deposited On:31 May 2022 20:45
Last Modified:31 May 2022 20:45

Repository Staff Only: item control page