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Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite

Nik Malek, Nik Ahmad Nizam and Ramli, Nur Isti'anah (2019) Preparation and antibacterial properties of cetylpyridinium bromide modified silver-loaded kaolinite. Materials Research Express, 6 (9). ISSN 2053-1591

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Official URL: http://dx.doi.org/10.1088/2053-1591/ab2e52


A system of dual antibacterial agents loaded onto kaolinite (Kao) as carrier has been developed by attaching cetylpyridinium bromide (CPB) onto Ag-loaded Kao (Ag-Kao). The analysis of CPB adsorbed onto Ag-Kao and characterisation of the CPB-Ag-Kao systems using X-ray diffraction (XRD), energy-dispersive X-ray (EDX) spectroscopy and Fourier-transform infrared (FTIR) spectroscopy demonstrated that the CPB molecules attached onto Ag-Kao and no changes occurred in the Kao structure. The antibacterial effect of different amounts of CPB and Ag attached onto Kao was investigated against Gram-positive (Staphylococcus aureus ATCC 6538) and Gram-negative (Escherichia coli ATCC 11229) bacteria. The antibacterial activity of CPB-Ag-Kao was higher than that of Ag-Kao and the highest antibacterial activity was recorded for CPB-Ag-Kao loaded with 50% Ag and 1000% CPB, which satisfied the cation exchange capacity of Kao. The higher antibacterial activity of CPB-Ag-Kao against a wide spectrum of bacteria was due to the synergistic effects of the two antibacterial agents loaded onto Kao as carrier.

Item Type:Article
Uncontrolled Keywords:energy dispersive x-ray, staphylococcus aureus, synergistic effect
Subjects:Q Science > Q Science (General)
ID Code:89179
Deposited By: Yanti Mohd Shah
Deposited On:26 Jan 2021 16:49
Last Modified:26 Jan 2021 16:49

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