Universiti Teknologi Malaysia Institutional Repository

A simulation study of cell separation in microfluidic channel based on hydrodynamic principle

Ahmad, M. R. and Mansor, M. A. and Ahmad, I. L. (2019) A simulation study of cell separation in microfluidic channel based on hydrodynamic principle. In: 2018 IEEE EMBS Conference on Biomedical Engineering and Sciences, IECBES 2018, 3-6 Dec 2018, Borneo Convention Centre Kuching Demak-Isthmus Bridge, Jalan Keruing, Sejingkat Kuching, Malaysia.


Official URL: https://dx.doi.org/10.1109/IECBES.2018.8626646


Separation micro-particles based on physical characteristics is important in numerous applications such as diagnostics, biological analyses, food industries and chemical processing. Microfluidic devices have emerged as a multifunctional and powerful platform for separation ranging from nano-micro sized particles to biological cells. This paper presents a simulation study for microparticle separation in a microfluidic channel based on hydrodynamic technique. By exploiting the hydrodynamic properties of the fluid flow and physical characteristics of microparticles, effective size-based separation is demonstrated. The objectives of the simulations are to obtain the appropriate channels’ angle to separate micro-particle. The analysis of effects of taper angle for microparticle separation was carried out using numerical solutions from the finite element ABAQUS-FEA software. The taper angles 20ºand 25ºare successfully separate the mixture of 1000 kgm-3 and 10000 kgm-3 density microparticle.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:cell separation, finite element, hydrodynamic
Subjects:T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:Electrical Engineering
ID Code:88545
Deposited By: Narimah Nawil
Deposited On:15 Dec 2020 18:31
Last Modified:15 Dec 2020 18:31

Repository Staff Only: item control page