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Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction

Mohammad, Nor Azizah and Abang Zaidel, Dayang Norulfairuz and Muhamad, Ida Idayu and Abdul Hamid, Mariani and Yaakob, Harisun and Mohd. Jusoh, Yanti Maslina (2019) Optimization of the antioxidant-rich xanthone extract from mangosteen (Garcinia mangostana L.) pericarp via microwave-assisted extraction. Heliyon, 5 (10). e02571-e02571. ISSN 2405-8440

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Official URL: http://dx.doi.org/10.1016/j.heliyon.2019.e02571

Abstract

Total phenolic content (TPC) and antioxidant properties of xanthone extract from mangosteen pericarp via microwave-assisted extraction (MAE) method was optimized by response surface methodology (RSM). The MAE extraction conditions to obtain optimum antioxidant-rich xanthone extract were at 2.24 min of irradiation time, 25 mL/g of solvent-to-solid ratio and 71% of ethanol concentration. The predicted results for four responses were as follows; 320.31 mg gallic acid equivalent/g extract, 83.63% and 93.77% inhibition (DPPH (2,2-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-Azino-bis-3-ethylbenzthiazoline-6-sulfonic acid) assays), and 144.56 mg Trolox equivalent/g extract (FRAP, Ferric reducing antioxidant power). The predicted and actual values were statistically insignificant (P > 0.05). Therefore, these results confirmed that the examined model was acceptable and relevant. MAE led to a slightly similar antioxidant capacity and a higher extraction of α-mangostin, a major xanthone of mangosteen pericarp as compared to water bath-maceration technique.

Item Type:Article
Uncontrolled Keywords:Antioxidant, Bioactive compound
Subjects:T Technology > TP Chemical technology
Divisions:Chemical and Energy Engineering
ID Code:87598
Deposited By: Widya Wahid
Deposited On:30 Nov 2020 17:04
Last Modified:30 Nov 2020 17:04

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