Universiti Teknologi Malaysia Institutional Repository

Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds

Jaganathan, S. K. and Mani, Mohan Prasath and Ayyar, M. and Rathanasamy, Rajasekar (2019) Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds. Polymer Testing, 78 . p. 105955. ISSN 0142-9418

[img]
Preview
PDF
1MB

Official URL: http://dx.doi.org/10.1016/j.polymertesting.2019.10...

Abstract

Bone tissue scaffolds require appropriate properties conducive for new tissue growth. In this study, we prepared a novel electrospun nanofiber scaffold using polyurethane (PU), rosemary (RM) oil and copper sulphate (CuSO4) respectively. The properties of the developed membranes were established through scanning electron microscopy (FESEM), atomic force microscopy (AFM), attenuated total reflectance Fourier-transform infrared spectroscopy (ATR-FTIR), thermal gravimetric analysis (TGA), contact angle and mechanical testing. Further, blood compatibility and cytocompatibility assay were carried out to evaluate their biological responses. The developed composites rendered appropriate surface morphology with tailor made wettability and roughness. Composites with engineered physicochemical properties improved the blood and cytocompatible properties which can be potentially exploited for bone tissue engineering applications.

Item Type:Article
Uncontrolled Keywords:Polyurethane, RM/CuSO4
Subjects:Q Science > Q Science (General)
Divisions:Biosciences and Medical Engineering
ID Code:87588
Deposited By: Widya Wahid
Deposited On:30 Nov 2020 09:04
Last Modified:30 Nov 2020 09:04

Repository Staff Only: item control page