A flexible optical sensor for microalbuminuria spectroscopy

Abstract

A flexible optical sensor unit was developed for the detection of albumin level in human urine. It consists of polydimethylsiloxane thinfilm with the microscopic glass as the substrate. A gradual increase of albumin level may indicate signs of health problem such as diabetes, hypertension, and endothelial dysfunction. The experimental results showed there are a spectral shift and an increase in absorbed light increase in intensity of light with sodium urate at different concentration as a substitute of urine sample. The transmittance and reflection of PDMS was determined in the 400–1400 nm wavelength range using halogen-detrium as the excitation light source to predict the sensor sensitivity based on the Beer–Lambert law. The results exhibited that the light intensity increases as the concentration of the sodium urate increases. This performance of prototype sensor ignites an alternative for albumin detection using flexible structure.