Universiti Teknologi Malaysia Institutional Repository

Morphological, thermal, and blood-compatible properties of electrospun nanocomposites for tissue engineering application

Manikandan, Ayyar and Mani, Mohan P. and Jaganathan, Saravana Kumar and Rajasekar, Rathanasamy (2018) Morphological, thermal, and blood-compatible properties of electrospun nanocomposites for tissue engineering application. Polymer Composites, 39 . E132-E139. ISSN 0272-8397

Full text not available from this repository.

Official URL: http://dx.doi.org/10.1002/pc.24463

Abstract

In this work, the morphological, thermal, and blood compatibility properties of prepared polyurethane (PU) and gandharvahasthadi eranda thailam (GHT) nanocomposites were investigated. Morphological and thermal characterization revealed reduced diameter, improved surface roughness, and higher thermal degradation compared to control. The activated partial thromboplastin time (APTT) and prothrombin time (PT) assay revealed that the fabricated nanocomposites displayed delayed blood clotting time owing to improved surface morphology. The hemolytic assay suggested that nanocomposites would be nonhemolytic material due to low hemolytic index of about 1.15% compared to pure PU (2.733%) portraying its safety with the red blood cells. Thus, the newly developed PU/GHT composite scaffold possessing better physicochemical and blood compatibility may be considered as a potential substitute scaffold for replacing damaged tissue. POLYM. COMPOS., 39:E132–E139, 2018.

Item Type:Article
Uncontrolled Keywords:morphological, thermal
Subjects:T Technology > T Technology (General)
Divisions:Biosciences and Medical Engineering
ID Code:85468
Deposited By: Widya Wahid
Deposited On:30 Jun 2020 16:45
Last Modified:30 Jun 2020 16:45

Repository Staff Only: item control page