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Biotechnological aspects and pharmaceutical applications of bacterials proteases

Aladdin, Azzam and Abd. Alsaheb, Ramzi A. and Pareek, Avnish and Othman, Nor Zalina and Abd. Malek, Roslinda and El Enshasy, Hesham A. (2017) Biotechnological aspects and pharmaceutical applications of bacterials proteases. Der Pharmacia Lettre, 9 (2). pp. 9-20. ISSN 0975-5071

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Abstract

Proteases enzymes are capable of hydrolyzing peptide bonds in proteins. They can be found in all living organisms. Bacterial proteases enzymes have great pharmaceutical importance due to their key role in biological processes and in the life-cycle of many pathogens. New technologies for rationally protein engineering proteases, as well as improved delivery options, will expand greatly the potential pharmaceutical applications of enzymes. Proteases are extensively applied agents in several sectors of pharmaceutical industry. Furthermore, numerous research applications predominant use of proteases has been in killing tumor cells, they are also emerging as useful agents in the treatment of digestive disorders, inflammation, and other diseases. The aim of this paper is to review the biotechnological aspects of proteases enzymes and summarize their pharmaceutical applications in the life sciences.

Item Type:Article
Uncontrolled Keywords:Bacterial proteases, protein engineering, pharmaceutical applications
Subjects:T Technology > TP Chemical technology
Divisions:Chemical Engineering
ID Code:84513
Deposited By: Fazli Masari
Deposited On:29 Feb 2020 20:29
Last Modified:29 Feb 2020 20:29

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