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Effect of span 60, labrasol, and cholesterol on Labisia pumila loaded niosomes quality

Ya’akob, Harisun and Siew Chin, C. and Abd. Aziz, A. and Ware, I. and Abd. Jalil, M. Fauzi and Ahmed, N. Rashidah and Sabtu, R. (2017) Effect of span 60, labrasol, and cholesterol on Labisia pumila loaded niosomes quality. International Journal of Biotechnology and Bioengineering, 11 (7). pp. 521-524.

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Official URL: https://dx.doi.org/10.5281/zenodo.1131531

Abstract

Labisia pumila (LP) plant extract has the potential to be applied in cosmeceutical products due to its anti-photoaging properties. The main purpose of this study was to improve transdermal delivery of LP by encapsulating LP in niosomes. Niosomes loaded LPs were prepared by coacervation phase separation method using non-ionic surfactant (Span 60), labrasol, and cholesterol. The optimum formula obtained were Span 60, labrasol and cholesterol at the mole ratio of 6:1:4. At the optimum formulation, the niosome obtained significantly improved the quality of transdermal penetration of LP compared to free LP.

Item Type:Article
Uncontrolled Keywords:Labisia pumila, niosomes, transdermal, quality
Subjects:T Technology > TP Chemical technology
Divisions:Chemical Engineering
ID Code:81525
Deposited By: Fazli Masari
Deposited On:23 Aug 2019 13:21
Last Modified:23 Aug 2019 13:21

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