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Chemical profiling and biological properties of Neolitsea kedahense gamble essential oils

Jani, N. A. and Sirat, H. M. and Ahmad, F. and Mohamad Ali, N. A. and Jamil, M. (2017) Chemical profiling and biological properties of Neolitsea kedahense gamble essential oils. Natural Product Research, 31 (23). pp. 2793-2796. ISSN 1478-6419

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Abstract

Hydrodistillation of the fresh stem and leaf of Neolitsea kedahense Gamble, collected from Gunung Jerai, Malaysia followed by the GC-FID and GC-MS analysis revealed the detection of a total of 47 constituents of which 28 (86.4%) from the stem and 31 (96.4%) constituents from the leaf. δ-Cadinene (17.4%), 1-epi-cubenol (11.8%), cyperotundone (9.0%), cis-cadin-4-en-7-ol (7.7%), τ-cadinol (7.1%) and α-cadinol (7.1%) were the principle constituents in the stem oil, whereas β-caryophyllene (18.9%), bicyclogermacrene (18.6%) and trans-muurola-4(14),5-diene (9.8%) were the major constituents in the leaf oil. Among the identified constituents, three constituents namely 7-epi-α-selinene, junenol and cis-cadin-4-en-7-ol have not been found previously from Neolitsea oils. The stem and leaf oils were screened for their α-glucosidase inhibitory and antibacterial activities. Both oils displayed potential α-glucosidase inhibitory activity, while the stem oil possessed weak antibacterial activity against Bacillus subtilis.

Item Type:Article
Uncontrolled Keywords:antibacterial, Neolitsea kedahense Gamble, ?-glucosidase inhibitory
Subjects:Q Science > QD Chemistry
Divisions:Science
ID Code:76984
Deposited By: Fazli Masari
Deposited On:30 Apr 2018 14:30
Last Modified:30 Apr 2018 14:30

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