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Epstein-barr virus positive primary sinonasal nasopharyngeal-type undifferentiated carcinoma: a distinct entity

Zahedi, Farah Dayana and Nik Hussin, Nik Mohd. Hazleigh and Husain, Salina and Kumar, Ramesh and Gendeh, Balwant Singh (2017) Epstein-barr virus positive primary sinonasal nasopharyngeal-type undifferentiated carcinoma: a distinct entity. Eastern Journal of Medicine, 22 (2). pp. 70-73. ISSN 1301-0883

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Official URL: https://www.journalagent.com/ejm/pdfs/EJM-76486-CA...

Abstract

Primary sinonasal nasopharyngeal-type undifferentiated carcinoma (PSNPC) is a rare variant of the sinonasal undifferentiated carcinoma (SNUC). The histological classification has implications on its management. We report a case of a 32 year old lady who presented with progressive nasal obstruction due to a sinonasal tumour. Endoscopic excision was performed and examination confirmed PSNPC with positive Epstein Barr virus in-situ hybridisation. Identification and recognition of PSNPC as a separate clinicopathological entity from SNUC is important as it dictates the management of this rare variant. Immunohistochemical analysis is invaluable in this endeavor.

Item Type:Article
Uncontrolled Keywords:sinonasal, undifferentiated carcinoma
Subjects:Q Science > QH Natural history
Divisions:Biosciences and Medical Engineering
ID Code:76101
Deposited By: Widya Wahid
Deposited On:24 Sep 2018 09:22
Last Modified:24 Sep 2018 09:22

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