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Fabrication and characterization of chitosan coated and uncoated pcl/ha/ppy composite scaffoldsusing freeze drying technique

Ufere, Sharon Kalu Joseph and Sultana, Naznin (2016) Fabrication and characterization of chitosan coated and uncoated pcl/ha/ppy composite scaffoldsusing freeze drying technique. ARPN Journal of Engineering and Applied Sciences, 11 (24). pp. 14052-14055. ISSN 1819-6608

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Abstract

Chitosan is an abundantly common, naturally occurring, polysaccharide biopolymer. In this study, chitosan was used to coat previously fabricated conductive Polycaprolactone/Hydroxyapatite/Polypyrrole (PCL/HA/PPY) composite scaffold and the properties of the coated and non-coated scaffolds were investigated and compared. The morphology of the chitosan coated and non-coated scaffolds were characterized using a scanning electron microscope (SEM). The wettability was determined using a water contact angle measuring system. Furthermore, water uptake was determined by measuring the water absorption of each sample before and after coated with chitosan. Water contact angle result revealed an increase in wettability of the scaffolds ranging from 108° ± 4.2 down to 59.4° ± 0.7. On the other hand, the coated sample showed a higher water uptake than the non-coated sample. The results indicated that coating with chitosan was important to increase water absorption of composite scaffold, rendering it more hydrophilic.

Item Type:Article
Uncontrolled Keywords:3D scaffolds, Bone tissue engineering, Chitosan, Coated
Subjects:Q Science > QH Natural history
Divisions:Biosciences and Medical Engineering
ID Code:74238
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:28 Nov 2017 15:42
Last Modified:28 Nov 2017 15:42

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