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Modelling and simulation of blood circulation towards mitral valve replacement risk calculation

Hoflin, V. and Soesanto, A. M. and Andriantoro, H. and Suriyanto, E. and Haueisen, J. (2016) Modelling and simulation of blood circulation towards mitral valve replacement risk calculation. In: 4th International Conference on Instrumentation, Communications, Information Technology and Biomedical Engineering, ICICI-BME 2015, 2-3 Nov 2015, Bandung, Indonesia.

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The operative mortality of a mitral valve replacement surgery in patients who suffer from a rheumatic heart disease and who have a concurrent pulmonary arterial hypertension accounts for 15 to 31 %. The complexity of the disease and of the cardiovascular system itself makes it difficult to find a specific reason for the high operative mortality. In a first approach to this problem we modelled and simulated the blood circulation under normal and diseased conditions. Herewith, the blood circulation can be analysed as a whole in spite of its complexity. For this purpose, we decided to model with the help of an electrical circuit analogy because it is not spatially dependant, fast and computational economic. The model includes the systemic and the pulmonary blood circulation with the main vessel-types. Hereby, we used the Multisim software to model and simulate. Simulation results show that our model matches the theoretical mitral flow patters from other resources. This model has positive signs to be used for a mitral valve replacement risk classification.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:Blood Circulation, Lumped Parameter Model, Mitral Valve Replacement, Rheumatic Heart Disease, Simulation
Subjects:Q Science > QH Natural history
Divisions:Biosciences and Medical Engineering
ID Code:73438
Deposited By: Mohd Zulaihi Zainudin
Deposited On:23 Nov 2017 09:37
Last Modified:23 Nov 2017 09:37

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