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Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties

Iqbal, Nida and Abdul Kadir, M. R. and Iqbar, Saman and Abd. Razak, Saiful Izwan and Rafique, M. Shahid and Bakhsheshi-Rad, H. R. and Idris, Mohd. Hasbullah and Khattak, M. A. and Raghavendran, H. R. B. and Abbas, A. A. (2016) Nano-hydroxyapatite reinforced zeolite ZSM composites: a comprehensive study on the structural and in vitro biological properties. Ceramics International, 42 (6). pp. 7175-7182. ISSN 0272-8842

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Official URL: http://dx.doi.org/10.1016/j.ceramint.2016.01.107

Abstract

The bioactive composite of hydroxyapatite and zeolite-ZSM5 was successfully synthesized via the cost effective microwave wet precipitation method. The structural and morphological features were studied by X-ray diffraction, FT-IR spectroscopy and TEM/EDX analysis. These tests revealed the presence of zeolite and hydroxyapatite in the zeolite-HA composites. Spherical particles, 76-88±20 nm in size, were visible on the TEM. The simulated body fluid SBF results in vitro verified the ability of the composites to support and accelerate the growth of the HA. Furthermore, the MTT assay showed the viability of normal human osteoblasts (NHOst) on the composite, up to seven days of culture. The cell adhesion and proliferation of the normal human osteoblast (NHOst) cells onto the disc surface was much higher than the control. Overall, the ZSM-HA samples composite nanostructure can be a considered potential candidate for biomedical application.

Item Type:Article
Subjects:Q Science > QH Natural history > QH426 Genetics
Divisions:Biosciences and Medical Engineering
ID Code:70041
Deposited By: Narimah Nawil
Deposited On:06 Nov 2017 14:20
Last Modified:20 Nov 2017 16:52

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