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Recent progress in the hydrophilic modification of alumina membranes for protein separation and purification

Ishak, Noor Fauziyah and Hashim, N. Awanis and Othman, Mohd. Hafiz Dzarfan and Monash, Purushothaman and Mohamed Zuki, Fathiah (2017) Recent progress in the hydrophilic modification of alumina membranes for protein separation and purification. Ceramics International, 43 (1). pp. 915-925. ISSN 0272-8842

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Official URL: https://doi.org/10.1016/j.ceramint.2016.10.044

Abstract

In general, alumina membranes have been extensively developed for protein separation and purification. Alumina membranes, which naturally feature a moderate hydrophilic character (contact angle of 40–50°) and the lowest cost among other oxide materials, are most suitable for these applications. Membrane fouling occurs due to the deposition and adsorption of proteins on the surface and pore walls of alumina membranes. This is one of the major issues that prevent the applicability of alumina membranes. Therefore, it is important to minimise membrane fouling by enhancing the hydrophilic character of the membranes as well as reducing interactions between proteins and the membranes surface. This review discusses the surface modification of alumina membranes in an effort to enhance the hydrophilic character of the membranes. Moreover, the introduction of graphene derivatives in modifying the hydrophilicity of alumina is also addressed. The superhydrophilic character of the alumina surface has a major influence on its anti-fouling and permeate flux properties, thus it improves the performance of the protein separation and purification processes.

Item Type:Article
Additional Information:RADIS System Ref No:PB/2017/11876
Uncontrolled Keywords:alumina membrane, surface modification
Subjects:T Technology > TP Chemical technology
Divisions:Chemical Engineering
ID Code:66138
Deposited By: Widya Wahid
Deposited On:11 Jul 2017 15:51
Last Modified:11 Jul 2017 15:51

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