Universiti Teknologi Malaysia Institutional Repository

Technological advancements in characterizing single cell's stiffness properties- A review

Ahmad, I. L. and Ahmad, M. R. (2015) Technological advancements in characterizing single cell's stiffness properties- A review. In: 3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014, 8 - 10December 2014, Kuala Lumpur, Malaysia.

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Official URL: http://dx.doi.org/10.1109/IECBES.2014.7047483

Abstract

Biophysical properties of living cells certainly play important roles for intra and intercellular biological events. However, conventional population approaches obscured cells heterogeneity and assume all cells are similar. With the introduction of single cell analysis, this limitation is slowly rectified by defining crucial methods to further revealing cell-to-cell variability. Research in biomechanics leads to better elucidation of cellular and molecular changes due to disease progression i.e diseased cell exhibits different mechanical properties as compared to healthy ones. This paper highlights on various technological advancements available for single cell stiffness characterizations and analytical comparison of the reviewed methods will be thoroughly discussed. In addition, several applications intended for early disease detection were presented.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:technological advancements, single cell stiffness
Subjects:T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:Electrical Engineering
ID Code:59497
Deposited By: Haliza Zainal
Deposited On:18 Jan 2017 01:50
Last Modified:19 Aug 2021 04:56

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