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Two-stage robust estimators for product concentration in a penicillin fermentation

Chow, A. W. and Ahmad, Arshad (2004) Two-stage robust estimators for product concentration in a penicillin fermentation. In: 18th Symposium of Malaysian Chemical Engineers (SOMChe) 2004, 13 - 14 Dec. 2004, UTP, Perak, Malaysia.



Two strategies are proposed for inferential estimations of penicillin concentration in a fed-batch fermentation process. The first scheme employs a partial least squares (PLS)-based estimator to directly estimate the intended product concentration. The second introduces a two-step estimation where biomass concentration is first estimated and used as the input to the final estimator along with other process variables. The results confirmed the strength of the two-stage approach. To further extend the capability of the estimation scheme, a wavelet-based filter is added to the estimation model. The improved performance obtained proved the efficacy of the wavelet filter.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:inferential estimation, penicillin fermentation, wavelet
Subjects:T Technology > T Technology (General)
Divisions:Chemical and Natural Resources Engineering
ID Code:5944
Deposited By: Norhani Jusoh
Deposited On:28 Jul 2008 07:56
Last Modified:10 Sep 2017 08:29

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