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Antioxidant Activities of Methanol Extract and Solvent Fractions of Marine Macroalga, Avrainvillea Erecta (Berkeley) a. Gepp and E.S. Gepp (Dichotomosiphonaceae)

Chai, Tsun Thai and Kwek, Meng Tee and Ismail, Nor Ismaliza Mohd and Ooi, Jillian Lean Sim and Amri, Affendi Yang and Abd. Manan, Fazilah and Law, Yew Chye and Wong, Fai Chu (2015) Antioxidant Activities of Methanol Extract and Solvent Fractions of Marine Macroalga, Avrainvillea Erecta (Berkeley) a. Gepp and E.S. Gepp (Dichotomosiphonaceae). Tropical Journal Of Pharmaceutical Research, 14 (3). pp. 503-509. ISSN 1596-5996

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Abstract

2O2) scavenging assays as well as ferric reducing antioxidant power (FRAP) assay. Total phenolic and flavonoid contents were determined spectrophotometrically. Results: CF and BF possessed equally high DPPH scavenging activity with half-maximal effective concentration (EC50) of 535 and 532 mg/ml, respectively. CF had stronger NO scavenging activity (EC50 743 µg/mL) than ME and BF, although weaker compared with quercetin (EC50 279 µg/ml). CF also produced the highest FRAP value (451 µmol Fe2+/g) among all samples examined. Notably, H2O2 scavenging activity was only found in CF (EC50 387 µg/ml), which was as strong (p > 0.05) as that of gallic acid (EC50 456 µg/mL). BF had the highest total phenolic content while CF had the highest total flavonoid content. Conclusion: CF of A. erecta, which has the highest flavonoid content of all the extracts evaluated, is a potential source of natural antioxidants, especially hydrogen peroxide scavengers.

Item Type:Article
Uncontrolled Keywords:antioxidant, avrainvillea erecta, flavonoid, macroalga, phenolic
Subjects:A General Works
ID Code:57836
Deposited By: Haliza Zainal
Deposited On:04 Dec 2016 12:07
Last Modified:09 Mar 2017 14:25

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