Universiti Teknologi Malaysia Institutional Repository

Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram

Mokri, Siti Salasiah and Saripan, M. I. and Marhaban, Mohammad Hamiruce and Nordin, Abdul Jalil and Hashim, Suhairul (2015) Hybrid registration of PET/CT in thoracic region with pre-filtering PET sinogram. Radiation Physics and Chemistry, 116 . pp. 300-304. ISSN 0969-806X

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Official URL: http://dx.doi.org/10.1016/j.radphyschem.2015.01.02...


The integration of physiological (PET) and anatomical (CT) images in cancer delineation requires an accurate spatial registration technique. Although hybrid PET/CT scanner is used to co-register these images, significant misregistrations exist due to patient and respiratory/cardiac motions. This paper proposes a hybrid feature-intensity based registration technique for hybrid PET/CT scanner. First, simulated PET sinogram was filtered with a 3D hybrid mean-median before reconstructing the image. The features were then derived from the segmented structures (lung, heart and tumor) from both images. The registration was performed based on modified multi-modality demon registration with multiresolution scheme. Apart from visual observations improvements, the proposed registration technique increased the normalized mutual information index (NMI) between the PET/CT images after registration. All nine tested datasets show marked improvements in mutual information (MI) index than free form deformation (FFD) registration technique with the highest MI increase is 25%

Item Type:Article
Uncontrolled Keywords:hybrid demon registration, multi-modalitie
Subjects:Q Science > QC Physics
ID Code:55624
Deposited By: Fazli Masari
Deposited On:22 Sep 2016 01:22
Last Modified:15 Feb 2017 03:30

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