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Arterial hemodynamics in patent ductus arteriosus stenting

Jamalruhanordin, Fara Lyana (2015) Arterial hemodynamics in patent ductus arteriosus stenting. Masters thesis, Universiti Teknologi Malaysia, Faculty of Biosciences and Medical Engineering.


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Cyanotic congenital heart disease (CHD) is the condition when insufficient blood transported throughout the whole body due to anomalies of blood vessels or heart. Hence, the procedure of maintaing the patency of ductus arteriosus were introduced where the stent is implanted at ductus arteriosus that should be closed naturally within 48 hours after the birth. The main purpose of this study is to investigate the hemodyamic effect of patent ductus arteriosus (PDA) after different types of stent design were implanted. Three different types of commercial stent design were used in this study: Closed Cell V stent, Palmaz-Schatz stent and Type One stent. The hemodynamic effect were investigated numerically via computational fluid dynamics by using ANSYS 14.0 software. Three hemodynamics variables were analysed in this study which are wall shear stress (WSS), oscillatory shear index (OSI) and relative residence time (RRT). Each stent affect the hemodynamic within PDA differently. The higher percentage of TAWSS exposed in range of 0.5 Pa to 2 Pa is better shown by Closed Cell V stent with 25.4%. Type One stent shown a good result in OSI which has high percentages exposed below 0.2 with the value of 34%. Palmaz-Schatz stent present a preferable results in both WSS low, 1.2% (low the better) and RRT within range of 10 Pa^-1 at 97.7%. Thus, this study can be useful in stent selection for PDA stenting.

Item Type:Thesis (Masters)
Additional Information:Thesis (Sarjana Kejuruteraan Bioperubatan) - Universiti Teknologi Malaysia, 2015; Supervisor : Dr. Ahmad Zahran Md. Khudzari
Uncontrolled Keywords:congenital heart disease (CHD), patent ductus arteriosus (PDA)
Subjects:R Medicine > R Medicine (General)
Divisions:Biosciences and Medical Engineering
ID Code:53856
Deposited By: Muhamad Idham Sulong
Deposited On:30 Mar 2016 03:54
Last Modified:08 Sep 2020 08:03

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