Tan, Jully and Foo, Dominic Chwan Yee and Kumaresan, Sivakumar and Abdul Aziz, Ramlan (2005) Evaluation of pharmaceutical cream production debottlenecking schemes. In: International Symposium On Design, Operation and Control Of Chemical Processes 2005, 13-15 August 2005, Seoul, Korea.
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Abstract
The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%.
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Uncontrolled Keywords: | Batch, modelling, optimisation, throughput, scheduling |
| Subjects: | T Technology > T Technology (General) |
| Divisions: | Chemical and Natural Resources Engineering |
| ID Code: | 5366 |
| Deposited By: | Norhani Jusoh |
| Deposited On: | 31 Mar 2008 09:09 |
| Last Modified: | 01 Jun 2010 15:29 |
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