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Chemopreventive effect of apple and berry fruits against colon cancer

Jaganathan, Saravana Kumar and Vellayappan, Muthu Vignesh and Narasimhan, Gayathri and Supriyanto, Eko and Dewi, Dyah Ekashanti Octorina and Narayanan, Aqilah Leela T. and Balaji, Arunpandian and Subramanian, Aruna Priyadarshini and Yusof, Mustafa (2014) Chemopreventive effect of apple and berry fruits against colon cancer. World Journal of Gastroenterology, 20 (45). pp. 17029-17036. ISSN 1007-9327


Official URL: http://dx.doi.org/10.3748/wjg.v20.i45.17029


Colon cancer arises due to the conversion of precancerous polyps (benign) found in the inner lining of the colon. Prevention is better than cure, and this is very true with respect to colon cancer. Various epidemiologic stud-ies have linked colorectal cancer with food intake. Apple and berry juices are widely consumed among various ethnicities because of their nutritious values. In this review article, chemopreventive effects of these fruit juices against colon cancer are discussed. Studies dealing with bioavailability, in vitro and in vivo effects of apple and berry juices are emphasized in this article. A thorough literature survey indicated that various phenolic phytochemicals present in these fruit juices have the innate potential to inhibit colon cancer cell lines. This review proposes the need for more preclinical evidence for the effects of fruit juices against different colon cancer cells, and also strives to facilitate clinical studies using these juices in humans in large trials. The conclusion of the review is that these apple and berry juices will be possible candidates in the campaign against colon cancer

Item Type:Article
Uncontrolled Keywords:apple, berry, chemoprevention, colon cancer, fruit juices, phytochemicals
Subjects:R Medicine > RC Internal medicine
Divisions:Biosciences and Medical Engineering
ID Code:52117
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:01 Feb 2016 03:53
Last Modified:17 Sep 2018 03:47

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