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Antimicrobial flavonoids from Artocarpus anisophyllus miq. and Artocarpus lowii King

Jamil, Shajarahtunnur and Abdul Athiff, Siti Mariam and Abdullah, Siti Awanis and Jemaon, Noraini and Mohd. Sirat, Hasnah (2014) Antimicrobial flavonoids from Artocarpus anisophyllus miq. and Artocarpus lowii King. Jurnal Teknologi, 71 (1). pp. 95-99. ISSN 0127-9696

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Official URL: http://dx.doi.org/10.11113/jt.v71.2699

Abstract

Antimicrobial activities of flavonoids isolated from the leaves and heartwoods of Artocarpus anisophyllus Miq. and Artocarpus lowii King were evaluated. Gram positive bacteria (Staphylococcus aureus and Bacillus cereus), Gram negative bacteria (Escherichia coli and Pseudomonas putida) and fungi (Candida albicans and Candida glabrata) were used in this study. Disc diffusion method was used as the qualitative assay while minimum inhibitory concentration and minimum microbicidal concentration methods were used as the quantitative assays. Artocarpin (8) showed strong antimicrobial activity towards all bacteria with inhibition zone diameter more than 11 mm and minimum microbicidal concentration value of 0.45 mg/mL. Isobavachalcone (3) exhibited strong antibacterial activity towards Gram positive bacteria with minimum microbicidal concentration value of 0.45 mg/mL. The findings of this study revealed that the isolated flavonoids from A. anisophyllus and A. lowii have potential to be developed as antimicrobial agents

Item Type:Article
Uncontrolled Keywords:Antimicrobial activity, flavonoids, Artocarpus anisophyllus, Artocarpus lowii
Subjects:Q Science
Divisions:Science
ID Code:51874
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:01 Feb 2016 11:53
Last Modified:27 Aug 2018 11:41

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