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Antimicrobial and anti-inflammatory activities of Piper porphyrophyllum (Fam. Piperaceae)

Ahmad, Farediah and Emrizal, Emrizal and M.Sirat, Hasnah and Jamaludin, Fadzureena and Mustapha, Nik Musa’adah and M.Ali, Rasadah and Arbain, Dayar and Aboul-Enein, Hassan Y. (2014) Antimicrobial and anti-inflammatory activities of Piper porphyrophyllum (Fam. Piperaceae). Arabian Journal of Chemistry, 7 (6). pp. 1031-1033. ISSN 1878-5352


Official URL: https://doi.org/10.1016/j.arabjc.2010.12.032


The crude extracts and isolated compounds of Piper porphyrophyllum (Piperaceae) were evaluated for antibacterial and anti-inflammatory activities. The ethyl acetate extract and 3′,4′,5,7-tetramethoxyflavone exhibited the highest activity against Staphylococcus aureus giving values of MIC = 62.5 and 250 μg/mL, respectively. 5-Hydroxy-7-methoxyflavanone and 4′,5-dihydroxy-3′,7-dimethoxyflavone were active against Pseudomonas aeruginosa, both with MIC value 125 μg/mL. The hexane extract and 4′,5-dihydroxy-3′,7-dimethoxyflavone gave the highest anti-inflammatory activity in in vitro quantitative lipoxygenase inhibition assay with inhibitory activity of (IE) 99.72% and 91.81%, respectively.

Item Type:Article
Uncontrolled Keywords:Piper porphyrophyllum extracts, flavonoids, antibacterial, anti-inflammatory
Subjects:Q Science
ID Code:51873
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:01 Feb 2016 11:52
Last Modified:27 Aug 2018 11:41

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