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Chemical constituents of the leaf of Alpinia mutica roxb

Mohd. Sirat, Hasnah and Jani, Nor Akmalazura (2013) Chemical constituents of the leaf of Alpinia mutica roxb. Natural Product Research, 27 (16). pp. 1468-1470. ISSN 1478-6419

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Official URL: http://dx.doi.org/10.1080/14786419.2012.718772


Hydrodistillation of the fresh leaves of Alpinia mutica afforded 0.005% colourless essential oil. GC and GC-MS analysis revealed the presence of 33 components accounting for 92.9% of the total oil, dominated by 20 sesquiterpenes (76.7%) and 10 monoterpenes (8.3%). The major constituent was found to be -sesquiphellandrene which was 29.2% of the total oil. Soxhlet extraction, followed by repeated column chromatography of the dried leaves yielded two phenolic compounds, identified as 5,6-dehydrokawain and aniba dimer A, together with one amide assigned as auranamide. The structures of these compounds were determined by using spectroscopic analysis. Antibacterial screening of the essential oil, the crude and isolated compounds showed weak to moderate inhibitory activity.

Item Type:Article
Uncontrolled Keywords:β-sesquiphellandrene, 56-dehydrokawain, alpinia mutica, aniba dimer a, auranamide, leaf oil composition
Subjects:Q Science > QD Chemistry
ID Code:50549
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:02 Dec 2015 10:08
Last Modified:28 Jan 2019 12:30

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