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Porous biodegradable metals for hard tissue scaffolds: a review

Yusop, A. H. and Bakir, A. A. and Shaharom, N. A. and Abdul Kadir, Mohammed Rafiq and Hermawan, Hendra (2012) Porous biodegradable metals for hard tissue scaffolds: a review. International Journal of Biomaterials, 2012 . pp. 1-10. ISSN 1687-8787

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Official URL: https://www.hindawi.com/journals/ijbm/2012/641430/

Abstract

Scaffolds have been utilized in tissue regeneration to facilitate the formation and maturation of new tissues or organs where a balance between temporary mechanical support and mass transport (degradation and cell growth) is ideally achieved. Polymers have been widely chosen as tissue scaffolding material having a good combination of biodegradability, biocompatibility, and porous structure. Metals that can degrade in physiological environment, namely, biodegradable metals, are proposed as potential materials for hard tissue scaffolding where biodegradable polymers are often considered as having poor mechanical properties. Biodegradable metal scaffolds have showed interesting mechanical property that was close to that of human bone with tailored degradation behaviour. The current promising fabrication technique for making scaffolds, such as computation-aided solid free-form method, can be easily applied to metals. With further optimization in topologically ordered porosity design exploiting material property and fabrication technique, porous biodegradable metals could be the potential materials for making hard tissue scaffolds.

Item Type:Article
Uncontrolled Keywords:Magnesium, biodegradable magnesium
Subjects:R Medicine > R Medicine (General)
Divisions:Biosciences and Medical Engineering
ID Code:33465
Deposited By: Fazli Masari
Deposited On:28 Aug 2013 09:40
Last Modified:14 Oct 2018 16:19

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