Analysis on rigidity of mitral valve leaflet (MVL) and backflow problems during cardiac cycle

Abstract

Problems that occur in the mitral valve are now worrying an increasing number of patients each day. In the mitral valve, regional variations in structure and material properties combine to affect the biomechanics of the entire valve. Previous studies have shown that the mitral valve leaflet tissue is highly extensible. The objective of this study was to investigate the relationship between the rigidity of mitral valves leaflet and backflow problems. Two stages of mitral valves analysis systolic and diastolic condition and also with and without ventricle were investigated. 2D models of the mitral valve leaflet (MVL) were created in ADINA-FSI for computational fluid dynamic analysis. The results show a linear relationship between rigidity of the mitral valves leaflet and volume of backflow. In conclusion, these computational techniques are very useful in the study of both mitral valve leaflet disease and failure of prostheses.