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Protein refolding in an oscillatory flow reactor

Lee, CT and Mackley, MR and Stonestreet, P and Middelberg, APJ (2001) Protein refolding in an oscillatory flow reactor. Biotechnology Letter, 23 . pp. 1899-1901.

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Official URL: http://www.springerlink.com/content/v5260w06736w7h...


We demonstrate that an oscillatory flow reactor is a viable reactor for protein refolding via direct dilution. The mixing characteristics of the oscillatory flow reactor are well described and controllable and, importantly, can be scaled-up to process scale without a loss of mixing efficiency. This makes the oscillatory flow reactor an attractive alternative to conventional stirred-tank reactors for process-scale renaturation.

Item Type:Article
Subjects:T Technology > TP Chemical technology
Divisions:Chemical and Natural Resources Engineering
ID Code:3114
Deposited By: Mohd Nazlee Faisal
Deposited On:18 May 2007 09:35
Last Modified:01 Jun 2010 03:07

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