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Effects of vitamin E supplementation on bone metabolism in nicotine treated rats

Hakim Ismail, Lokman and Mohammad, Norazlina and Ahmad, Nazrun and Lee, Phe Ling and Ima-Nirwana, Ima-Nirwana (2008) Effects of vitamin E supplementation on bone metabolism in nicotine treated rats. In: Clinical Engineering and Its Application. Penerbit UTM , Johor, pp. 81-97. ISBN 978-983-52-0558-3

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Official URL: http://smj.sma.org.sg/4803/4803a2.pdf


Bone is a unique connective tissue which constantly undergoes remodelling. Bone remodelling involves bone formation by osteoblasts and bone resorption by osteoclasts. Serum osteocalcin and urine deoxypyridinoline (DPD) are among the specifi c biochemical markers used to measure bone formation and bone resorption activities, respectively.(1,2) Cytokines such as interleukin-1 (IL-1) and interleukin-6 (IL-6) are called bone-resorbing cytokines and play a major role in bone resorption.(3) The bone matrix is composed of organic and inorganic components. The organic components include collagen and glycoprotein while the inorganic components include minerals such as calcium and phosphorus. Both the organic and inorganic components provide rigidity and strength to the bone.

Item Type:Book Section
Subjects:Q Science > QH Natural history > QH301 Biology
T Technology > TP Chemical technology
ID Code:19355
Deposited By: Zalinda Shuratman
Deposited On:04 Jan 2012 09:55
Last Modified:11 Jul 2017 02:48

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