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Reverse micelle extraction

Mohd. Setapar, Siti Hamidah (2007) Reverse micelle extraction. In: Advances in Separation Processes. Penerbit UTM , Johor, pp. 135-153. ISBN 978-983-52-05958-8

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Reverse micelle is an alternative method to conventional separation and purification procedures due to their potential for large scale use (Ono et al., 1996; Naoe et al., 2004; Shen and Yu, 2007; Moore and Palepu, 2007), their potential application to continuous separation of biological substances (Zhang et al., 1999; Hong and Kuboi, 1999; Naoe et al., 2002; Noh and Imm, 2005; Juang et al., 2006; Majumdar and Mahapatra, 2007), the process similarities to liquid-liquid extraction (Naoe et al., 2004; Hasmann et al., 2007), and easy scale-up (Chang et al., 1997; Rodrigues et al., 1999; Kilikian et al., 2000; Mathew and Juang, 2007). Nishiki et al. (1998) showed that reverse micelle extraction is able to recover proteins with little denaturation because proteins can be hosted in a solubilised aqueous phase which is shielded from the organic solvent by surfactant molecules; solubilisation inside reverse micelle does not damage the native protein structure (Yu et al., 2003; Hetch and Peled, 2006). Therefore, in an ordinary liquid-liquid extraction, although it has been difficult to extract large bioactive molecules such as proteins, the limitation can be overcome by utilising a nanostructural molecular assembly like reverse micelle (Aires-Barros and Cabral, 1991; Ono et al., 1996).

Item Type:Book Section
Subjects:Q Science > QD Chemistry
Divisions:Chemical and Natural Resources Engineering
ID Code:14052
Deposited By: Liza Porijo
Deposited On:17 Aug 2011 07:59
Last Modified:17 Aug 2011 07:59

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