eprintid: 921
rev_number: 46
eprint_status: archive
userid: 43
dir: disk0/00/00/09/21
datestamp: 2007-02-23 09:16:51
lastmod: 2010-06-01 02:49:20
status_changed: 2007-02-23 09:16:50
type: book_section
metadata_visibility: show
contact_email: pollyna@yahoo.com
item_issues_count: 0
creators_name: Mohd Bohari, Siti Pauliena
creators_name: Hamid, Muhajir
creators_name: Shaari, Khozirah
creators_name: Lajis, Nordin
creators_id: pollyna@yahoo.com
creators_id: muhajir@biotech.upm.my
creators_id: 
creators_id: 
title: GLUCOSE UPTAKE :Stimulatory Activity of Gynura procumbens in 3T3- F442A adipocytes 
ispublished: pub
subjects: RM
divisions: FacultyofScience
full_text_status: public
monograph_type: technical_report
abstract: Gynura procumbens (Compositae) has been used as folk remedy for the treatment to control diabetes mellitus and hyperlipidemia. The aim of this study was to examine whether G. procumbens extract for various solvent system had an enhancing effect on glucose uptake in 3T3 adipocyte cell lines. At the concentration 0.1mg/mL of hexane fraction showed increase in glucose uptake activity 4.5 fold whereas  etyl acetate fraction increased 2.2 fold at 0.005 mg/mL of compare to untreated. For butanol fraction showed dependent manner of insulin and at 0.05mg/mL of extract, glucose uptake activity was increased 1.4 fold compare to the insulin.These results suggest that the antidiabetic action of G. procumbens may be mediated throught the stimulation of glucose uptake and the potentiation of insulin action.
date: 2006
date_type: published
publisher: UNIMAS and  Malaysian Natural Products Society
place_of_pub: Sarawak
pages: 4
institution: Universiti Putra Malaysia
department: Department of Microbiology
refereed: TRUE
isbn: 983-9257-7
book_title: Malaysian Medicinal Plant: Chemistry and Biological Activity
citation:   Mohd Bohari, Siti Pauliena and Hamid, Muhajir and Shaari, Khozirah and Lajis, Nordin  (2006) GLUCOSE UPTAKE :Stimulatory Activity of Gynura procumbens in 3T3- F442A adipocytes.   In:  Malaysian Medicinal Plant: Chemistry and Biological Activity.   UNIMAS and Malaysian Natural Products Society, Sarawak.  ISBN 983-9257-7     
document_url: http://eprints.utm.my/921/1/Glucose_uptake_paper.pdf