Universiti Teknologi Malaysia Institutional Repository

Mathematical modeling of an amperometric glucose sensor: the effect of membrane permeability and selectivity on performance

Abd. Aziz, Azila (2009) Mathematical modeling of an amperometric glucose sensor: the effect of membrane permeability and selectivity on performance. Jurnal Teknologi (Kejuruteraan) (51F). pp. 77-94. ISSN 0127-9696

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Official URL: http://www.penerbit.utm.my/onlinejournal/51/F/51si...

Abstract

Interference from electro-active chemicals such as ascorbic acid, uric acid and acetaminophen can be a problem for peroxide based glucose biosensors. Most works focused on the employment of a perm-selective membrane sandwiched between the electrode and the active component of the sensor to overcome this problem. In this work, a mathematical model has been developed to study the effect of membrane permeability and selectivity on peroxide based glucose biosensor performance. Digital simulation was carried out using the finite difference method. As expected, membrane selectivity to peroxide played a major role in interference reduction. However, interestingly, the model also suggested that the manipulation of the transport properties of the protective outer layer would also result in acceptable interference reduction.

Item Type:Article
Uncontrolled Keywords:Glucose biosensors; mathematical modeling; acetaminophen; interferents; transport properties
Subjects:T Technology > TP Chemical technology
Divisions:Chemical and Natural Resources Engineering (Formerly known)
ID Code:9995
Deposited By: Pn Norhayati Abu Ruddin
Deposited On:16 Jul 2010 04:20
Last Modified:22 Jul 2010 02:04

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