Microwave synthesis and antibacterial studies of bioceramics doped with antibacterial metal

Abstract

The aim of this work was to evaluate the effect of zinc metal ion on the antibacterial properties of bioceramics i.e. hydroxyapatite for the protection of bacterial infections. In this paper, rapid icrowave synthesis of hydroxyapatite with different weightages of antibacterial ions zinc (2 and 4 wt%) at 850 watts via microwave irradiation method at 10 mins was reported. The synthesized bioceramics were chemically characterized using energy dispersive X-ray (EDAX) and Fourier transform infrared spectroscopy (FTIR) studies. FT-IR analysis revealed the presence of Zn into HA lattices due to the increasing in the vibrational modes corresponds to phosphates and hydroxyl groups and EDAX analysis confirmed the presence of oxygen (O), calcium (Ca), phosphor (P), and zinc (Zn) in the ZnHA samples. Antibacterial studies have demonstrated that each of the Zn-bearing bioceramics samples exhibits marked antibacterial effects against Bacillus subtilis and Pseudomonas aeruginosa. Based on the results, it can be concluded that the synthesized Zn HA bioceramics have potential to prevent the bacterial infections and can be used as bone tissue regeneration.