Phytochemical screening, isolation of coumarins and examining bioactivity of Prangos platychlaena Boiss. plant IN Iraq

Abstract

The Prangos platychlaena Boiss. a wild plant belonging to the Apiaceae family, is a native plant of Kurdistan-Iraq. The roots, leaves, stem and flowers of the plant were collected in the Halgurd mountain of the Kurdistan region of Iraq, and extracted by petroleum ether, ethanol and water to obtain the crude extracts. Our results showed that the plant contains different phytochemicals that are distributed unequally in different parts. The chromatography technique was used for the isolation and purification of three coumarins (5,8-dimethoxy psoralen, 5-methoxy psoralen and 8-methoxy psoralen) from the parts of the flower, all compounds are new among the Prangos species. The extracts of different plant parts and isolated compounds showed anti-oxidant and anti-microbial activities against pathogenic bacteria and yeasts. These findings suggested that this plant, specially their leaves and flowers can be used for the treatment of some diseases in the future.