Universiti Teknologi Malaysia Institutional Repository

Experimental comparison of initial pool generation for direct-proportional length-based DNA computing

Khalid, Marzuki and Ibrahim, Z. S. and Muhammad, M. S. and Tsuboi, Y. and Ono, O. (2007) Experimental comparison of initial pool generation for direct-proportional length-based DNA computing. In: IEEE Region 10 Annual International Conference, Proceeding/TENCON 2007, art. No. 4085068, 21-24 Nov. 2005, Melbourne, Qld..

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Official URL: http://dx.doi.org/10.1109/TENCON.2005.301238

Abstract

Previously, direct-proportional length-based DNA computing (DPLB-DNAC) for solving weighted graph problems such as the shortest path problem, has been proposed. After the initial pool generation, the initial pool is subjected to amplification, by polymerase chain reaction (PCR), and finally, the output of the computation can be visualized by gel electrophoresis. In this paper, we give more attention to the initial pool generation of DPLB-DNAC. For this purpose, two kinds of initial pool generation methods, which are hybridization/ligation and parallel overlap assembly (POA) are evaluated. We found that both of the methods can be successfully employed to generate the initial pool generation of DPLB-DNAC, as supported by results of actual experiments. However, POA is more preferable than that of hybridization-ligation in term of population size and generation time.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:initial pool, direct-proportional length-based DNA computing
Subjects:T Technology > TK Electrical engineering. Electronics Nuclear engineering
Divisions:Electrical Engineering
ID Code:8653
Deposited By: Ms Zalinda Shuratman
Deposited On:02 Dec 2009 09:32
Last Modified:08 Nov 2011 04:49

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