Elsayed, E. A. and Moussa, S. A. and El-Enshasy, H. A. and Wadaan, M. A. (2020) Anticancer potentials of zinc oxide nanoparticles against liver and breast cancer cell lines. Journal of Scientific and Industrial Research, 79 (1). pp. 56-59. ISSN 0022-4456
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Abstract
The aim of the present study was to evaluate the in vitro cytotoxic effects of zinc oxide nanoparticles (ZnONPs) with particle size of 40 and 50 nm against human hepatocellular carcinoma and human breast cancer cell lines. The effects of nanoparticles were analyzed after 24 hours of incubation using standard MTT assay. Incubation of ZnONPs with different cells produced a dose-dependent inhibition of cell growth. The IC50 values of ZnONPs for both prepared samples (40 and 50 nm) were comparable. It has been noticed that MCF-7 and MDA cells were more affected by the prepared 50 nm than the 40 nm ZnONPs. On the other hand, HepG2 cells showed inverse relation in terms of their response to the size of the prepared NPs.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | cancer cells, in vitro, nano-biotechnology |
| Subjects: | T Technology > TP Chemical technology |
| Divisions: | Chemical and Energy Engineering |
| ID Code: | 86447 |
| Deposited By: | Narimah Nawil |
| Deposited On: | 08 Sep 2020 13:18 |
| Last Modified: | 09 Sep 2020 07:20 |
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