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UTMGO : a tool for searching a group of semantically related gene ontology terms and application to annotation of anonymous protein sequence

Deris, Safaai and Alashwal, H. and Othman, M. R. (2006) UTMGO : a tool for searching a group of semantically related gene ontology terms and application to annotation of anonymous protein sequence. International Journal of Biological and Medical Sciences, 1 (2). pp. 111-119. ISSN 1307-7457

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Official URL: http://www.waset.org/ijbms/v1.html

Abstract

Gene Ontology terms have been actively used to annotate various protein sets. SWISS-PROT, TrEMBL, and InterPro are protein databases that are annotated according to the Gene Ontology terms. However, direct implementation of the Gene Ontology terms for annotation of anonymous protein sequences is not easy, especially for species not commonly represented in biological databases. UTMGO is developed as a tool that allows the user to quickly and easily search for a group of semantically related Gene Ontology terms. The applicability of the UTMGO is demonstrated by applying it to annotation of anonymous protein sequence. The extended UTMGO uses the Gene Ontology terms together with protein sequences associated with the terms to perform the annotation task. GOPET, GOtcha, GoFigure, and JAFA are used to compare the performance of the extended UTMGO.

Item Type:Article
Uncontrolled Keywords:anonymous protein sequence, gene ontology, protein sequence annotation, protein sequence alignment
Subjects:Q Science > QA Mathematics > QA75 Electronic computers. Computer science
Divisions:Computer Science and Information System (Formerly known)
ID Code:8452
Deposited By:INVALID USER
Deposited On:04 May 2009 08:53
Last Modified:02 Jun 2010 01:55

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