Finite element simulation, characterization and transportation of magnetic nanoparticles under the impact of magnetic field in blood vessels

Abstract

The drug delivery research based on magnetic particles has two major components. The first one discusses the preparation; characteristics and reaction of magnetic nanoparticles for the purpose of the transportation of the drug and the second part represents the drug delivery design for managing the dynamic of magnetic nano particles from injected positon to targeted area of vascular system. This study of the two parts of magnetic particles of drug delivery deals with preparation, Characterization, Synthesis and transportation of nano magnetic particles under the effect of external magnetic field in blood vessels. Co-precipitation method has been used for synthetization of nano crystalline Fe3O4 samples. The structural characterization and morphology of this sample has been done by using X-ray diffraction and Bruker D8 Advance X-ray diffractometer and Field Emission Scanning Electron Microscopy. After the study of preparation and characterization, the transportation of nano magnetic particles is explored under the effect of external magnetic field through a mathematical model. It is determined that the effect of external magnetic field through in constant fluid pressure, speed, distance of magnet and magnetic saturation is significantly affected by controlling the magnetic system that is required for an operative system of drug delivery. The non- dimensional partial differential equations are solved by using finite element method and they conclude that under the effect of external magnetic field, the flow parameters presents a significant role for the investigation of the pattern of nano magnetic particles and blood.