Ja'afar, M. K. and Jamil, S. and Basar, N. and Bakar, M. B. and Sarker, S. D. and Flanagan, K. J. and Senge, M. O. (2017) Lactones and flavonoids isolated from the leaves of globimetula braunii. Natural Product Communications, 12 (9). pp. 1455-1458. ISSN 1934-578X
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Abstract
The dried powdered leaves of Globimetula braunii (Engler) Van Tiegh were effectively extracted by the cold extraction method. Purification of the EtOAcsoluble and MeOH-soluble extracts successfully yielded two lactones namely (R)-6-[(S)-2-hydroxy-4-(4-hydroxyphenyl)butyl]-5,6-dihydropyran-2-one (dodoneine) 1 and (1R,5S,7S)-[2-(4-hydroxyphenyl)ethyl]-2,6-dioxabicyclo[3.3.1]-nonan-3-one (2), together with five flavonoids namely quercetin 3, (+)-catechin 4, quercitrin 5, rutin 6 and avicularin 7. Their structures were established by spectroscopic means, and the absolute configuration of compound 1 was confirmed by X-ray analysis.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Dodoneine, Flavonoids, Globimetula braunii, Lactones, X-ray crystallography |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Science |
| ID Code: | 77118 |
| Deposited By: | Fazli Masari |
| Deposited On: | 30 Apr 2018 14:43 |
| Last Modified: | 30 Apr 2018 14:43 |
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