Jaganathan, S. K. and Balaji, A. and Mohandas, H. and Sivakumar, G. and Kasi, P. and Selvakumar, M. and Kadiman, S. B. and Srinivasan, A. and Mohd. Faudzi, A. A. B. and Supriyanto, E. and Mandal, M. (2017) Hemocompatibility of sulfuric acid-treated metallocene polyethylene and its application in reducing the quantity of medical plastic waste. Polymer - Plastics Technology and Engineering, 56 (3). pp. 240-253. ISSN 0360-2559
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Abstract
The hazards of dumping medical plastics have created a huge demand to reduce the quantity of plastic usage without compromising its quality. The metallocene synthesized polyethylene is one such advent, however, its clinical usage is limited by the problem of hemocompatibility. This study investigates the effect of sulfuric acid-induced changes in metallocene polyethylene. Fourier transform infrared spectroscopy analysis illustrated the addition of OH and sulfonic acid group, which subsequently increased the wettability. An improvement in micro as well as nanosurface roughness was observed. Ultimately, the treated surfaces depicted delayed clotting time, adsorption of specific plasma proteins, reduced hemolysis, and resistance against platelet adhesion.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Biocompatible polymers, blood compatibility, coagulation pathways, metallocene polyethylene, platelet adhesion, protein adsorption, sulfuric acid treatment, surface properties |
| Subjects: | T Technology > TP Chemical technology |
| Divisions: | Biosciences and Medical Engineering |
| ID Code: | 77047 |
| Deposited By: | Fazli Masari |
| Deposited On: | 30 Apr 2018 14:36 |
| Last Modified: | 30 Apr 2018 14:36 |
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