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Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones

Ming, L. S. and Jamalis, J. and Al Maqtari, H. M. and Rosli, M. M. and Sankaranarayanan, M. and Chander, S. and Fun, H. K. (2017) Synthesis, characterization, antifungal activities and crystal structure of thiophene-based heterocyclic chalcones. Chemical Data Collections, 9-10 . pp. 104-113. ISSN 2405-8300

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Abstract

Heterocyclic chalcones containing thiophene moiety were synthesized and their chemical structures determined via IR, MS, 1H NMR and 13C NMR spectroscopy. Crystal structure of the compounds was determined using single crystal X-ray diffraction.The chalcones were also screened for in-vitro antifungal activity against two fungal strains; Candida albicans (MTCC 3958) and Aspergillus niger (MTCC 9933)which gave good results.

Item Type:Article
Uncontrolled Keywords:Antifungal, Chalcones, Crystal structure, Heterocycle, Thiophene
Subjects:Q Science > QD Chemistry
Divisions:Science
ID Code:75480
Deposited By: Widya Wahid
Deposited On:28 Mar 2018 04:05
Last Modified:28 Mar 2018 04:05

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