Hemodynamic prediction in patent ductus arteriosus morphologies

Abstract

Patent ductus arteriosus (PDA) is a condition in which the ductus arteriosus remain opened after birth, causing the blood to shunt through from the aorta to the pulmonary artery. However, due to the complicated nature of the arterial geometry, the flow characteristic inside the PDA is not fully understood, since simplified model are commonly used in researches. This study aims to identify the hemodynamic characteristic in three different patient-specific morphologies. Computational modeling via computational fluid dynamic (CFD) is implemented to predict the blood flow behavior in different PDA morphologies. The result shows that low wall shear stress is observed at the region where the flow recirculation occurs. High wall shear stress is observed in the pulmonary artery due to increase of flow velocity at the insertion point of PDA. The PDA morphologies exhibit left-to-right shunt, which diverts approximately 10% of blood flow from the aorta to the pulmonary artery. The highest shunted blood flow is found in TR LPA morphology. High value of OSI indicates the changes of wall shear stress vector. It is observed that DS LPA has the highest area covered by OSI which presents better hemodynamic characteristic as compared to other morphology.