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Antioxidant and anti-inflammatory activities of essential oils of Actinodaphne macrophylla and A. pruinosa (Lauraceae)

Wan Salleh, Wan Mohd. Nuzul Hakimi and Ahmad, Farediah (2016) Antioxidant and anti-inflammatory activities of essential oils of Actinodaphne macrophylla and A. pruinosa (Lauraceae). Natural Product Communications, 11 (6). pp. 853-855. ISSN 1934-578X

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Abstract

The essential oils of Actinodaphne macrophylla and A. pruinosa were analyzed by GC and GC-MS and evaluated for their antioxidant and anti-inflammatory activities.The essential oil of the leaves of A. macrophylla was characterized by the presence of 31 components (78.2%), with germacrene B (16.8%) and globulol (16.0%) as the major components. A total of 28 components (71.6%) were characterized in the leaf oil of A. pruinosa with the most abundant components being globulol (17.8%) and spathulenol (12.0%). The antioxidant activity was determined by DPPH radical scavenging and total phenolic content, while anti-inflammatory activity by lipoxygenase assay. The essential oil of A. pruinosa demonstrated significant activity on DPPH (IC50 85.6 μg/mL), phenolic content (190.2 mg GA/g) and in the lipoxygenase (IC5085.2 μM) assays.

Item Type:Article
Uncontrolled Keywords:Actinodaphne macrophylla essential oil, Actinodaphne pruinosa essential oil, antiinflammatory agent, antioxidant, cadin 4 en 10 ol, delta cadinene, epi cubenol, essential oil, germacrene B, globulol, lipoxygenase, phenol derivative, plant medicinal product, sesquiterpene, spathulenol, t muurolol, unclassified drug, antiinflammatory agent, antioxidant, essential oil, vegetable oil, Actinodaphne macrophylla, Actinodaphne pruinosa, antiinflammatory activity, antioxidant activity, Article, controlled study, DPPH radical scavenging assay, drug determination, drug identification, drug screening, drug structure, enzymatic assay, IC50, Lauraceae, mass fragmentography, plant leaf, chemistry, Anti-Inflammatory Agents, Antioxidants, Gas Chromatography-Mass Spectrometry, Lauraceae, Oils, Volatile, Plant Oils
Subjects:Q Science > QD Chemistry
Divisions:Science
ID Code:74161
Deposited By: Siti Nor Hashidah Zakaria
Deposited On:28 Nov 2017 05:01
Last Modified:28 Nov 2017 05:01

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