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Effect of silver based products on simulated body fluid

Sanati, Parisa and Nik Malek, Nik Ahmad Nizam and Chua, Lee Suan (2014) Effect of silver based products on simulated body fluid. In: 2nd International Science Postgraduate Conference (ISPC 2014), 10-12 Mac, 2014, Skudai, Johor.

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Abstract

Silver Zeolite A, Silver clinoptilolite, and Silver bentonite are called Silver Based Products (SBPs) .They have been used for treating some types of infectious diseases as antibacterial agents. Gastric fluid is vital fluids in body.. The first aims of this study is to study the effect of SBPs on the pH changes of gastric fluids in different concentrations, however, studying the effects of simulated gastric fluid (SGF) as model of gastric fluid on the structures of SBPs was the second aim. Zeolites and clay were applied as the carrier materials which silver ion (Ag+) could attach to them and produce SBPs as antibacterial agents. SBPs are analyzed by EDX and FTIR spectroscopy. The effects of SBPs on (SGF) are studied in different concentrations. The chemical framework variations of SBPs are analyzed by FTIR spectroscopy after contact with SGF in different concentrations and the results shown, the most important structural peaks which are same as those parents. SBPs had some insignificant structural variations after contacted with SGF. With increasing concentration of SBPs to SGF, more changes are occurred on their structures. At last the pepsin activity in SGF is studied.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:silver, pepsin
Subjects:R Medicine > R Medicine (General)
Divisions:Biosciences and Medical Engineering
ID Code:61470
Deposited By: Fazli Masari
Deposited On:25 Apr 2017 08:25
Last Modified:25 Apr 2017 08:25

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