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Comparison of ethnic variations in skin physiological conditions and stratum corneum lipid compositions among Malaysians, Koreans, and Vietnamese

Hasham, Rosnani and Kim, Da Sel and Abdul Hamid, Mariani and Kim, Sun Ki and Park, Chang Seo (2014) Comparison of ethnic variations in skin physiological conditions and stratum corneum lipid compositions among Malaysians, Koreans, and Vietnamese. In: 5th International Conference on Biotechnology for the Wellness Industry, 10-11 Jun, 2014, Kuala Lumpur, Malaysia.

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Abstract

The understanding of ethnic variations in permeability barrier characteristic of the skin is important for the development of cosmetic product with a specialized formulation that fits well to the skin of the respective ethnic group. The aim of this study was to investigate the differences in skin physiological conditions and stratum corneum (SC) lipid properties in healthy three Asian ethnic groups (Malaysians, Koreans, and Vietnamese) that living in the same environment. Epidermal thickness was measured by confocal reflectance microscopy (CRM), and other skin conditions (transepidermal water loss (TEWL), skin pigmentation, SC hydration and sebum content) were analyzed using a multifunctional skin physiology monitor. SC lipids were extracted from the inner forearms by a cup method. Malaysians had the thickest epidermis, followed by Koreanand Vietnamese. The analysis of skin barrier function expressed in TEWL showed that Malaysian had the weakest skin barrier function compared to that of Vietnamese and Koreans. In addition, Malaysian skin was found to have high sebum content, but lowest SC lipid content than those of Koreans and Vietnamese. The HPTLC densitometry analysis also revealed that Malaysian having the lowest value of ceramide/cholesterol ratio ascompared with both Korean and Vietnamese. These differences were found to correlate with the higher TEWL in Malaysian skin. Higher amount of CER [NS]and [EOP], and lower amount of CER [NP], [ADS] and [AH] were also observed in Malaysian than that of Korean and Vietnamese. These find ings illustrate variations in skin physiological conditions and stratum corneum lipid properties among three Asian ethnic groups. Therefore, the present study contributes to a better understanding and diversity of Asian skin differences.

Item Type:Conference or Workshop Item (Paper)
Uncontrolled Keywords:epidermal thickness, skin barrier function
Subjects:T Technology > TP Chemical technology
Divisions:Chemical Engineering
ID Code:61237
Deposited By: Fazli Masari
Deposited On:22 Mar 2017 01:09
Last Modified:30 Aug 2017 04:57

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